Ozempic, the brand name for semaglutide, is an injectable medication primarily prescribed for individuals with type 2 ...
Testosterone and Medical Weight Loss?
Testosterone and weight loss, where’s the evidence?
Going back to basics, when consulting a medical specialist how you can lose a few inches or trim down a few pant sizes, you may have been told “Calories out has to exceed calories in”, excess calories consumed get converted to fat storage for future use by the body, simply eat less, and burn more energy and you’ll lose weight, right?
What this doesn’t account for is your ability to exercise, or burn additional calories, your metabolism, hormonal balance, dietary habits, and your body's efﬁciency with fat storage. Those with joint injuries, back pain, knee pain, or other conditions that can make it difﬁcult if not impossible to go for a 30-minute jog, or complete a 50-minute high-intensity training routine, 5-days a week. Not to mention the nagging of work or family obligations that compete for your free time to exercise consistently.
Researchers have long been testing novel ways to help with weight loss by altering the hormonal signals our body uses to trigger appetite, fat absorption, fat storage, along with ways to increase your basal metabolic rate. FDA-approved pills for weight loss usually offer only modest beneﬁts, which include signiﬁcant risks, and often see rebound weight gain once the medication has been discontinued.
Multiple other medications have been withdrawn from the market because of signiﬁcant side effects or lack of effectiveness.
Obesity is a true epidemic in this country, and impacts the quality of life, and decreases life expectancy. Obesity also carries its inherent risk for developing diabetes and all of its associated complications including heart disease and hypertension. So where does testosterone ﬁt into this equation?
As researchers have found, there is a link between obesity and low testosterone production, and “the implication of testosterone therapy in the management of obesity in men with Low-T is of paramount clinical signiﬁcance” according to one endocrinology journal article. Studies have also found that up to 50% of men with obesity have low testosterone, that percentage grew to as much as 75% in those awaiting bariatric surgery, further establishing the correlation between obesity and low testosterone.
The evidence lies with the multiple androgenic effects of testosterone itself, which exerts the effect on muscle, bone, joints, tendons, ligaments, and additional hormonal pathways within the body that help to direct the use of fat stores and maintain lean muscle mass.
Additional researchers have shown that achieving physiologically normal levels of testosterone, in previously deﬁcient subjects, and maintaining that level for the long term allows for signiﬁcant, progressive, sustained weight loss without relapse or rebound weight gain. Decreased obesity, improved blood pressure, fasting glucose, and cholesterol, testosterone supplementation aids the body in decreasing inﬂammation, improving erectile function, vigor and reducing fatigue.
These changes all contribute to an overall improvement in the quality of life. Now, the evidence is there, through established practices like Blokes Men's Health, it is now easier than ever to ﬁnd out if low testosterone is the contributing factor to your weight loss issues. Ask yourself the question, “Do I want a better quality of life?”
Jason Leep MD
Blokes Medical Consultant