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What are GLP-1 Drugs for Weight Loss?

By Josh Whalen
May 22, 2023

Are you struggling to lose weight? Do you find yourself constantly hungry and unable to resist the temptation of unhealthy foods? If so, you may be interested in GLP-1 drugs, a new class of medications that can help you lose weight by reducing your appetite.

What are GLP-1 Drugs?

Glucagon-like peptide 1 receptor agonists, or GLP-1 drugs, are medications that have similar effects to a hormone called GLP-1. GLP-1 is a hormone that is naturally produced by your body whenever you eat. GLP-1 stimulates the release of insulin, which helps your body regulate blood sugar levels. It also reduces appetite by sending signals to the brain that the body is full.

GLP-1 drugs have a similar effect by binding to GLP-1 receptors in the body. This stimulates the release of insulin and reduces appetite. The three most common GLP-1 drugs on the market today are Semaglutide, Wegovy, and Ozempic.

Semaglutide is a GLP-1 drug taken by injection once a week. Semaglutide has been approved by the FDA for weight loss in people with a body mass index (BMI) of 27+ who also have at least one weight-related health concern, like high blood pressure or type 2 diabetes. It works by reducing appetite and increasing feelings of fullness, which can help people eat less and lose weight.

Wegovy is a once-weekly injection that is similar to Semaglutide and has also been approved by the FDA for weight loss in people with a BMI of 27 or higher who have at least one weight-related health condition. It works in the same way as Semaglutide, by reducing appetite and increasing feelings of fullness.

Ozempic is a once-weekly injection that has been approved by the FDA for the treatment of type 2 diabetes but has also been found to be effective for weight loss. It works in the same way as Semaglutide and Wegovy, by reducing appetite and increasing feelings of fullness.

Are GLP-1 Drugs Effective for Weight Loss?

All three of these GLP-1 drugs have been shown to be effective for weight loss in clinical trials. In one study, people who took Semaglutide lost an average of 15% of their body weight over a 68-week period, while people who took a placebo lost just 2.4%. In another study, people who took Wegovy lost an average of 16.4% of their body weight over a 68-week period, while people who took a placebo lost just 5.7%. In a study of Ozempic, participants taking the GLP-1 drug lost an average of 5.7% of their body weight over a 28-week period, compared to just 0.7% for those who took a placebo.

Are GLP-1 Drugs Right for You?

GLP-1 drugs are generally well-tolerated, but like any medication, they can have side effects. The most common side effects of Semaglutide, Wegovy, and Ozempic are nausea, vomiting, and diarrhea, which typically go away after a few weeks of use. Some people may also experience low blood sugar, which can be dangerous if not treated.

If you’re considering GLP-1 drugs for weight loss, it is important to discuss them with a professional to determine if they are right for you. Contact our experts at Blokes for help determining if GLP-1 drugs are right for your weight loss goals.

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